49ers 26 (10-2) Rams 0 (2-10)
The 49ers defense pitched a shut out to keep San Francisco with the second best record in the league at 10-2 and lock up the division title. The 49ers defense, first in the league in points allowed and rushing yards allowed, held the Rams to 157 yards of total offense, including just 31 rushing yards, and no points. Alex Smith had two TD passes of over 50 yards, a 52-yarder to Michael Crabtree and a 56-yarder to Kyle Williams. Frank Gore added 21 carries for 73 yards to surpass Joe Perry as the 49ers all time leading rusher.
